中国寄生虫学与寄生虫病杂志

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纳米金在生物医学技术应用的研究现状

李家萌,曹颖,赵媛,杨毅梅*   

  1. 云南省大理大学基础医学院寄生虫学教研室,大理 671000
  • 出版日期:2016-04-30 发布日期:2016-06-30

Research Status of Application of Gold Nanoparticles in Medical Biotechnology

LI Jia-meng,CAO Ying,ZHAO Yuan,YANG Yi-mei*   

  1. Department of Parasitology,School of Basic Medicine,Dali University,Dali 671000,China
  • Online:2016-04-30 Published:2016-06-30

摘要: 近年来,纳米金因其独特的物理化学性质及生物学性质受到越来越广泛的关注,并逐渐被当作光学探针和生物相容性材料来使用。随着纳米金标记技术向医学领域的不断渗透,以纳米金为免疫标记物的检测技术将成为现代重要标记技术,也将会在未来基础医学和临床医学中得到广泛应用。本文综述了纳米金在病原体、核酸蛋白质检测和生物传感器制备等方面的最新研究进展。

关键词: 纳米金, 标记技术, 检测

Abstract: In recent years, gold nanoparticles(GNPs) have attracted more and more attention for their unique physical, chemical and biological properties, and are emerging as optical probes and biocompatibility materials for use. With the application of nanogold labeling technology in the medical field, detection techniques using GNPs as immune markers will become a major labeling technique, and will have wide applications in basic and clinical medicine. In this article, recent research progress on the applications of GNPs in the detection of pathogens, nucleic acids, and proteins and in the preparation of biosensors is reviewed.

Key words: Gold nanoparticle, Labeling technique, Detection