中国寄生虫学与寄生虫病杂志

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猪带绦虫基因组学及猪囊尾蚴病候选疫苗的研究进展

马承旭1,2 *,王宏伟1,2,杨艺萱1,2   

  1. 1甘肃中医药大学附属医院检验科,2甘肃省中医药防治慢性疾病重点实验室,兰州730000
  • 出版日期:2016-04-30 发布日期:2016-06-30

Research Progress on the Genomics of Taenia solium and Candidate Vaccines for Cysticercosis

MA Cheng-xu1,2 *, WANG Hong-wei1,2, YANG Yi-xuan1,2   

  1. 1 Department of Laboratory, Affiliated Hospital of Gansu University of Chinese Medicine; 2 Gansu Traditional Chinese Medicine Key Laboratory for Chronic Diseases, Lanzhou 730000, China
  • Online:2016-04-30 Published:2016-06-30

摘要: 基因组学、蛋白质组学、生物信息学的快速发展,以及分子生物学和免疫学等新技术的出现推动了猪囊尾蚴病的研究。本文就猪带绦虫基因组学的研究近况及猪囊尾蚴病的候选疫苗和抗原等进行综述,旨在为猪带绦虫基因组学研究及猪囊尾蚴病的防治提供新的思路,为开发新型、高效抗猪囊尾蚴病疫苗或筛选诊断用抗原分子提供有益的资料。

关键词: 基因组学, 猪带绦虫, 疫苗

Abstract: Research on cysticercosis has been stimulated by the rapid development of genomics, proteomics and bioinformatics and the emergence of molecular biological and immunological technologies. In this review, we attempt to discuss the research development on genomics of Taenia solium and candidate vaccines and antigens for cysticercosis. This will provide a new perspective for studying genomics of Taenia solium and for cysticercosis prevention and treatment, and provide a wealth of informative data for the development of novel and highly efficient vaccines against cysticercosis or diagnostic antigen molecules for cysticercosis.

Key words: Genomics, Taenia solium, Vaccine