中国寄生虫学与寄生虫病杂志

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肺部多发细粒棘球蚴病术后复发危险因素分析

孙久贺,孙清超,张铸,张昌明,邓彦超*   

  1. 新疆医科大学第一附属医院胸外科,乌鲁木齐 830054
  • 出版日期:2016-02-28 发布日期:2016-03-11

Risk Factors for Post-surgery Recurrence of Multiple Pulmonary Cystic Echinococcosis

SUN Jiu-he, SUN Qing-chao, ZHANG Zhu, ZHANG Chang-ming, DENG Yan-chao*   

  1. Department of Thoracic Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
  • Online:2016-02-28 Published:2016-03-11

摘要:

收集2005年1月至2014年10月在新疆医科大学第一附属医院胸外科行手术治疗的肺部多发细粒棘球蚴病病例的临床资料。以多因素Logistic回归分析肺部多发棘球蚴病术后复发的影响因素。73例肺部多发细粒棘球蚴病病例中,男性40例,女性33例,男女性别比为1.21 ∶ 1。平均年龄为37.6岁。所有病例均有畜牧区居住史或犬接触史,均行手术治疗,38例患者术后服用阿苯达唑片或阿苯达唑脂质体3个月至1年不等。复发6例,复发率为8.2%。多因素Logistic回归分析结果显示,术前棘球蚴包囊破裂为术后复发的危险因素,术后服用抗棘球蚴病药物为术后复发保护因素,可降低复发风险。

关键词: 肺部细粒棘球蚴病, 多发, 复发

Abstract:

Clinical information of patients with multiple pulmonary cystic echinococcosis who received surgery in the Department of Thoracic Surgery of the Hospital from January 2005 to October 2014 was collected. Multivariate logistic regression analysis was used to analyze the predisposing factors for post-surgery recurrence of multiple pulmonary cystic echinococcosis. Among the 73 cases of multiple pulmonary cystic echinococcosis, 40 were males and 33 were females, with a male-to-female ratio of 1.21 ∶ 1. The average age of patients was 37.6 years. All the patients reported a living history in pastoral areas or contacts with dogs. Thirty-eight patients were administered with albendazole tablets or liposomal albendazole for 3 to 12 months after surgery. Recurrence occurred in 6 cases, with a rate of 8.2%. Multivariate logistic regression analysis revealed the preoperative rupture of hydatid cyst to be the risk factor for post-surgery recurrence. The administration of anti-hydatid drugs after surgery plays a protective role against recurrence, and may reduce the risk of recurrence.

Key words: Lung hydatid disease, Multiple, Recurrence