动物寄生线虫遗传多样性的研究进展

中国寄生虫学与寄生虫病杂志

动物寄生线虫遗传多样性的研究进展

殷方媛1,2，李法财1,2，赵俊龙1，胡敏1 *

1华中农业大学，农业微生物学国家重点实验室，动物医学院，武汉430070；2中国农业科学院兰州兽医研究所，家畜疫病病原生物学国家重点实验室，甘肃省动物寄生虫病重点实验室，兰州730046

出版日期:2015-10-30 发布日期:2016-01-06

Research Progress on Genetic Diversity in Animal Parasitic Nematodes

YIN Fang-yuan1,2, LI Fa-cai1,2, ZHAO Jun-long1, HU Min1 *

1 State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070，China; 2 State Key Laboratory of Veterinary Etiological Biology, Gansu Province Key Laboratory of Animal Parasitic Diseases, Lanzhou Veterinary Research Institute, CAAS, Lanzhou 730046, China

Online:2015-10-30 Published:2016-01-06

摘要/Abstract

摘要：

动物寄生线虫分子遗传标记的发展对兽医寄生虫学中的基础和应用研究领域有着重要意义。通过对线虫种群遗传多样性的研究，不仅能够为抗药性等位基因的扩散提供理论依据，而且对线虫病防治策略的制定具有指导作用。因此，本文就分子遗传标记（RFLP、RAPD、PCR-SSCP、AFLP、SSR和线粒体DNA）在寄生线虫遗传多样性研究中的应用进行综述。

关键词: 动物寄生线虫, 遗传多样性, 分子遗传标记

Abstract:

The development of molecular genetic markers for parasitic nematodes has significant implications in fundamental and applied research in Veterinary Parasitology. Knowledge on genetic diversity of nematodes would not only provide a theoretical basis for understanding the spread of drug-resistance alleles, but also have implications in the development of nematode control strategies. This review discusses the applications of molecular genetic markers（RFLP, RAPD, PCR-SSCP, AFLP, SSR and mitochondrial DNA） in research on the genetic diversity of parasitic nematodes.

Key words: Animal parasitic nematode, Genetic diversity, Molecular genetic marker

殷方媛1,2，李法财1,2，赵俊龙1，胡敏1 *. 动物寄生线虫遗传多样性的研究进展[J]. 中国寄生虫学与寄生虫病杂志.

YIN Fang-yuan1,2, LI Fa-cai1,2, ZHAO Jun-long1, HU Min1 *. Research Progress on Genetic Diversity in Animal Parasitic Nematodes[J]. Chinese Journal of Parasitology and Parasitic Diseases.