中国寄生虫学与寄生虫病杂志 ›› 2013, Vol. 31 ›› Issue (4): 13-307-309.

• 现场研究 • 上一篇    下一篇

东洞庭湖区渔民血吸虫感染相关影响因素分析

喻鑫玲1,周杰1 *,何永康1,黄民主2,李岳生1   

  1. 1 湖南省血吸虫病防治所,血吸虫病免疫与传播控制湖南省重点实验室,湖南省血吸虫病诊断参比实验室,WHO湖区血吸虫病防治研究合作中心,岳阳 414000;2 中南大学公共卫生学院,长沙 410005
  • 出版日期:2013-08-30 发布日期:2013-12-27

Influence Factors of Schistosoma japonum Infection among Fishermen in Eastern Dongting Lake Region

YU Xin-ling1,ZHOU Jie1*,HE Yong-kang1,HUANG Ming-zhu2,LI Yue-sheng1   

  1. 1 Hunan Institute of Parasitic Diseases;Key Laboratory of Immune and Control Schistosomiasis of Hunan Province;Hunan Provincial Reference Laboratory for Schistosomiasis Diagnosis; WHO Collaborating Centre for Research and Control on Schistosomiasis in Lake Region, Yueyang 414000,China; 2 School of Public Health,Central South University,Changsha 410005,China
  • Online:2013-08-30 Published:2013-12-27

摘要: 目的  了解东洞庭湖区专业渔民血吸虫感染状况,并探讨其相关影响因素。  方法  于2009年在湖南省岳阳县抽取两个渔民聚集村的275名渔民为调查对象,进行血吸虫病病原学检查和问卷调查。对粪检阳性渔民作B超影像学检查。采用多因素非条件Logistic回归分析渔民血吸虫感染的影响因素。  结果  渔民血吸虫病人群感染率为40.4%(111/275),感染度几何均数为17.4±4.4;肝肿大率、脾肿大率、门脉扩张率和肝实质纤维化率分别为35.1%(39/111)、19.8%(22/111)、9.9%(11/111)和58.6%(65/111)。多因素非条件Logistic回归分析显示,影响东洞庭湖区渔民血吸虫病病情的因素有年龄(OR=0.630)、捕捞工作年限(OR=2.470)、化疗次数(OR=0.425)和2008年化疗情况(OR=0.290)(均P<0.01)。  结论  东洞庭湖区渔民血吸虫感染率与血吸虫病导致的肝脾损害依然严重,需进一步加强监测和控制措施。

关键词: 血吸虫病, 渔民, 影响因素, Logistic回归, B超

Abstract: Objective  To investigate schistosome infection among the professional fishermen in Yueyang County, East Dongting Lake Region and its influence factors.  Methods  A total of 275 fishermen from two fisherman villages in Yueyang County were selected in 2009. They were investigated by fecal examination and questionnairing. The stool-egg positive individuals were detected by B ultrasound. The multivariate unconditional Logistic regression analysis was used to explore the related factors of schistosome infection and liver in fishermen.  Results  The total infection rate in fishermen was 40.4%(111/275), and the geometric mean of EPG was 17.4±4.4. B ultrasound data showed among 111 egg positive individuals, 39(35.1%) cases manifested as hepatomegaly, 22(19.8%) had splenomegaly, 11(9.9%) had portal vein expansion and 65(58.6%) had hepatic fibrosis. Multivariate unconditional Logistic regression analysis showed that age groups(OR=0.630), fishing working years(OR=2.470), chemotherapy frequency(OR=0.425) and chemotherapy in 2008(OR=0.290) were the influence factors on schistosome infection(P<0.01).  Conclusion  Schistosome infection rate is high, Schistosoma japonicum-induced liver and spleen injuries are still severe in fisherman of Eastern Dongting Lake Region.

Key words: Schistosomiasis, Fisherman, Influence factor, Logistic regression, B ultrasound