中国寄生虫学与寄生虫病杂志 ›› 2011, Vol. 29 ›› Issue (2): 20-159-160,封三.

• 研究简报 • 上一篇    下一篇

杭州市余杭区慢性淋巴丝虫病患者生命质量调查

王来根*,胡永勤,唐爱奇,方杭燕,干伟群   

  1. 杭州市余杭区疾病预防控制中心,杭州 311100
  • 出版日期:2011-04-30 发布日期:2012-09-27

Investigation on Life Quality of Patients with Chronic Lymphatic Filariasis in Yuhang District of Hangzhou

WANG Lai-gen*,HU Yong-qin,TANG Ai-qi,FANG Hang-yan,GAN Wei-qun   

  1. Yuhang District Center for Disease Control and Prevention,Hangzhou 311100,China
  • Online:2011-04-30 Published:2012-09-27

摘要: 采用欧洲五维度健康量表(EQ-5D)对杭州市余杭区慢性丝虫病患者和健康人群(对照)进行生命质量研究。结果显示,共发出调查问卷600份,有效应答550份(91.7%),其中病例组276份、对照组274份。慢性丝虫病患者EQ-5D指数得分为0.770±0.128,对照人群为0.872±0.073。慢性丝虫病患者的行动、自我照顾、日常活动、抑郁/焦虑和疼痛/不舒服等5个维度问题报告率(43.8%、22.5%、44.9%、47.8%和29.0%)显著高于对照人群(6.6%、5.8%、12.0%、20.4%和10.6%)(P<0.01),关联强度(RR)分别为6.67、3.86、3.74、2.73和2.34。表明慢性丝虫病患者的生命质量低于健康人,主要表现在行动、自我照顾和日常活动等方面。

关键词: 慢性淋巴丝虫病, 患者, 生命质量

Abstract: Data were collected from chronic lymphatic filariasis patients and the public in Yuhang District of Hangzhou. Health status was assessed by using EuroQol (EQ)-5D. A total of 600 questionnaires were sent and 550 (91.7%) returned (276 chronic lymphatic filariasis patients and 274 members of the public). The EQ-5D index score for patients with chronic lymphatic filariasis (0.770±0.128) were lower than the general public (0.872±0.073). In contrast to the public(6.6%, 5.8%, 12.0%, 20.4%, and 10.6%), patients reported more problems with their mobility(43.8%), self-care(22.5%), daily activities (44.9%), anxiety/depression (47.8%), and pain/discomfort (29.0%) (P<0.01). Strength of association were 6.67, 3.86, 3.74, 2.73, and 2.34, respectively. These results indicated that chronic lymphatic filariasis shows an impact on patients′ health-related quality of life. It particularly causes great problems in the dimensions of mobility, self-care, and daily activities.

Key words: Chronic lymphatic filariasis, Patient, Life quality