中国寄生虫学与寄生虫病杂志 ›› 2009, Vol. 27 ›› Issue (3): 17-279.

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寄生虫感染对人体会有有利的一面吗?

尹卫东1, 杨亦青1, 张进顺2 *   

  1. 1 河北北方学院临床检验教研室, 张家口 075000; 2 河北北方学院寄生虫教研室, 张家口 075000
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-06-30 发布日期:2009-06-30
  • 通讯作者: 张进顺

Are Parasitic Infections Advantageous to Humans?

YIN Wei-dong1, YANG Yi-qing1, ZHANG Jin-shun2 *   

  1. 1 Department of Clinical Laboratory at Laboratory Medicine Faculty, Hebei North University, Zhangjiakou 075000, China; 2 Department of Parasitology, Hebei North University, Zhangjiakou 075000, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-06-30 Published:2009-06-30
  • Contact: ZHANG Jin-shun

摘要: 寄生虫感染可对人体造成不同程度的损害。但最新研究表明寄生虫感染对人体有有利的一面, 不仅可在一定程度上阻止炎症性肠病、糖尿病、自身免疫性疾病及过敏性疾病等的发生, 而且对研究这些疾病的发病机制, 以及寻求更安全有效的治疗策略起到了积极地推动作用。另外以秀丽隐杆线虫为模式生物, 在细胞信号转导、功能基因组学和药物筛选等生命科学研究领域取得了重大的突破。

关键词: 寄生虫, 炎症性肠病, 细胞凋亡, 糖尿病, 多发性硬化症, 哮喘

Abstract:

Humans are negatively affected by parasitic infection. However, recent researches

revealed that to some extent, parasitic infections are advantageous to humans. Parasitic infections

are found to benefit patients of inflammatory bowel disease, diabetes mellitus, autoimmune

disease and allergic disorder. Furthermore, they promoted studies on pathogenesis of these

diseases, and therefore on safe and effective therapeutic strategy.

In addition, by taking the Caenorhabditis elegans as model organism,

researchers have made a breakthrough in the area of life science, including signal transduction, functional genomics and drug screening.

Key words: Parasite, Inflammatory bowel disease, Apoptosis, Diabetes, Multiple sclerosis, Asthma