中国寄生虫学与寄生虫病杂志 ›› 2000, Vol. 18 ›› Issue (3): 14-172.

• 防治经验 • 上一篇    下一篇

湖北省黑热病流行态势的评估

桂爱芳 1;左胜利 1;吴锦华1;桂希恩2;胡乐群 1;杨连第1;张绍清1
  

  1. 湖北省医学科学院寄生虫病防治研究所!武汉430079 2湖北医科大学附二医院,武汉 430071
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2000-06-30 发布日期:2000-06-30

EVALUATION OF PREVALENT STATUS OF KALA-AZAR IN ENDEMIC AREA OF HUBEI PROVINCE *

GUI Ai-fang 1;ZUO Sheng-li 1;WU Jing-hua 1;GUI Xi-en 2;HU Le-qun 1;YANG Lian-di 1;ZHANG Shao-qing 1   

  1. 1 Institute of Parasitic Diseases;Hubei Academy of Medical Science;Wuhan 430079; 2 The 2nd Affiliated Hospital;Hubei Medical University,Wuhan 430071
  • Received:1900-01-01 Revised:1900-01-01 Online:2000-06-30 Published:2000-06-30

摘要:   [目的 ]复查湖北省自 1989年起陆续报告的 14例“黑热病”,及评估我省黑热病的流行现况。 [方法 ]复查“黑热病”患者的骨髓片、免疫学检查 (L DT、IFAT)、接种动物及真菌培养、媒介 (白蛉 )和保虫宿主 (犬 )的调查。[结果 ]除 1例输入的和 1例残存的皮肤型黑热病外 ,其余 12例为播散型荚膜组织胞浆菌病。1997~ 1999年在 9个地市的 2 3个县 (市 )的 2 5个乡镇进行了免疫学监测 ,对 13 890人采用利什曼素皮内试验 (L DT) ,阳性率 0 .0 0 7% ,40岁以下的人群无阳性。其中 175 6人作间接荧光抗体试验 (IFAT) ,结果均为阴性。在调查区内未发现中华白蛉。查犬 30 2只 ,未发现病犬。 [结论 ]湖北省已消灭黑热病 ,且防治成果巩固

关键词: 黑热病, 流行病学, LDT, IFAT, 荚膜组织胞浆菌病, 白蛉

Abstract:  Objective] To identify the diagnosis of 14 cases with “kala-azar” previously reported in Hubei Province since 1989 and to evaluate the present status of the disease. [Methods] Bone marrow smear, immunological test (LDTand IFAT), mouse inoculation, fungi culture, vector ( Phlebotomus ) and reservoir host (dog) survey. [Results] Among the 14 cases, 12 cases were progressive disseminated histoplasmois, one was an imported case and another one was a remnant skin type“kala-azar” case. An immunological survey was conducted during 1997~1999 in 25 townships located in 23 counties of 9 prefectures and cities. A total of 13 890 persons had been examined by LDT, the positive rate was 0.07% , no positive case was found among the persons under 40 years of age. During the survey, 1 756 persons had been examined by IFAT, the results were negative .No Phlebotomus chinensis had been found in the surveyed area . A total of 302 dogs were examined, no sick dog had been found. [Conclusion]Kala-azar has been eradicated in Hubei Province.

Key words: Kala-azar, epidemiology, LDT, IFAT, progressive disseminated histoplasmois, Phlebotomus.