中国寄生虫学与寄生虫病杂志 ›› 2000, Vol. 18 ›› Issue (3): 12-166.

• 论著 • 上一篇    下一篇

ELISA检测妇科肿瘤患者伴发弓形虫感染的调查

黄鹤;阎福华;李川江;赵美毅;汤俊文;李向荣
  

  1. 湖北省医学科学院病毒研究所!武汉430079 ;湖北省肿瘤医院妇科!武汉430079
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2000-06-30 发布日期:2000-06-30

DETECTION OF TOXOPLASMA INFECTION IN WOMEN WITH GYNAECOLOGIC NEOPLASMS USING ELISA 

HUANG He 1;YAN Fu hua 2;LI Chuan jiang 1;ZHAO Mei yi 2;TANG Jun wen 2;LI Xiang rong 2   

  1. 1 Institute of Virology;Hubei Academy of Medical Sciences;Wuhan 430079 2 Department of Gynaecology;Hubei Cancer Hospital;Wuhan 430079
  • Received:1900-01-01 Revised:1900-01-01 Online:2000-06-30 Published:2000-06-30

摘要:   [目的 ]了解妇科宫颈癌患者伴发弓形虫感染的情况。[方法 ]采用 EL ISA法检测弓形虫 Ig G、Ig M抗体和循环抗原。 [结果 ]宫颈癌、妇科良性肿瘤、其它疾患妇女 3组人群的弓形虫感染率分别为 :44 .0 % (2 2 / 5 0 )、2 5 .4% (15 / 5 9)和 2 0 .3% (2 8/ 138)。 3组人群 Ig G阳性率分别为 2 0 .0 0 %、11.86 %和 10 .87% ,Ig M阳性率分别为2 0 .0 0 %、13.5 6 %和 8.70 % ,循环抗原阳性率分别为 14.0 0 %、5 .0 9%和 1.45 %。 [结论 ]宫颈癌患者弓形虫感染率明显高于其它两组人群 ,以循环抗原和 Ig M阳性尤为明显

关键词: 弓形虫感染, 宫颈肿瘤, ELISA, 循环抗原, IgM, IgG

Abstract:  Objective] To understand the concurrent in Toxoplasma infection among women with cervical cancer. [Methods] The anti Toxoplasma IgG, IgM antibodies (Abs) and circulating antigens (CAg) in 247 sera ( from 50 cases with cervical cancer in group 1, 59 cases with gynaecological benign tumors in group 2 and 138 cases with other diseases in group 3 ) were detected by ELISA. [Results] The total positive rates of the CAg and the Abs in the three groups were 44 0% (22/50), 25 4% (15/59) and 20 3% (28/138), respectively. The positive rates were 20 0%, 11 9% and 10 9%, respectively for IgG 20 0%, 13 6% and 8 7%, respectively fot IgM and 14 0%, 5 1% and 1 4% respectively for CAg. [Conclusion] The Toxoplasma infection rate of the cervical cancer group was higher than those of the other two groups, particularly the positive rates of CAg and IgM.

Key words: Toxoplasma infection, cervical neoplasms, ELISA, circulating antigen, IgM, IgG.