中国寄生虫学与寄生虫病杂志 ›› 1994, Vol. 12 ›› Issue (1): 19-19.
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朱荫昌
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摘要： 应用等电聚焦技术将日本血吸虫可溶性虫卵抗原（SEA）分为20个不同等电点（pI）的组分（等电点范围为1．86—11．40），测定其各组分的体液与细胞免疫反应及体外诱发肉芽肿形成反应。结果表明等电点酸性区的组分（pI3．78－5．54）在日本血吸虫肉芽肿形成中可能起重要的作用；抗体，在感染的早期（5wk）也与肉芽肿的调节有关。
关键词: IEF, pI, fractions, SEA, Schistosoma, japonicum
Abstract: The soluble egg antigen of Schistosoma japonicum was fractionated into 20 individual isoelectric point (pI) fractions with different pIs ranging from 1.86-11.40 by isoelectric focusing (IEF). The fractions were tested for humoral and cellular responses, as well as in vitro granuloma formations.The results indicated that the fractions in the acidic region(pI 3.78-5.54)may play an important role in granuloma elicitation in schistosomiasis japonica,and antibodies are also involved in the regulation of granuloma formation especially at the early stage (5 week postinfection).
中图分类号:
R383.24
朱荫昌. 日本血吸虫可溶性虫卵抗原等电点组分的特性分析(英文)[J]. 中国寄生虫学与寄生虫病杂志, 1994, 12(1): 19-19.
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