中国寄生虫学与寄生虫病杂志 ›› 1990, Vol. 8 ›› Issue (1): 38-40.

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泡球蚴病和棘球蚴病患者血清IgG、IgA和IgM水平的比较

张京元,刘波,李燕宾,王浩,朱克安,孙忠贵,刘家祥,李明   

  1. 宁夏医学院寄生虫学教研室; 宁夏医学院寄生虫学教研室; 宁夏医学院寄生虫学教研室; 宁夏固原地区人民医院外科; 宁夏固原地区人民医院外科; 宁夏固原地区人民医院外科; 宁夏固原地区人民医院外科; 西吉县人民医院外科
  • 收稿日期:2017-01-09 修回日期:2017-01-09 出版日期:1990-02-28 发布日期:2017-01-09

COMPARISON OF SERUM IMMUNOGLOBULIN LEVELS IN PATIENTS WITH ALVEOLAR AND CYSTIC ECHINOCOCCOSIS

  • Received:2017-01-09 Revised:2017-01-09 Online:1990-02-28 Published:2017-01-09

摘要: 比较测定了91例泡球蚴病患者和83例棘球蚴病患者血清中IgG、IgA和IgM水平。泡球蚴病患者IgG、IgA和IgM水平及棘球蚴病患者IgG、IgM水平均非常显著地高于健康人。泡球蚴病患者IgG和IgM水平的几何均数各为棘球蚴病患者的1.67和1.25倍。IgG浓度在200IU/ml以上者,泡球蚴病患者非常显著地高于棘球蚴病患者,而IgM浓度在100IU/ml以上者,前者也显著地高于后者。用PPA-ELISA和ABC-ELISA检测的抗体效价中,只有IgG浓度和ELISA抗体效价间有显著相关(0.05P0.02)。

关键词: 泡球蚴病, 棘球蚴病, 血清免疫球蛋白

Abstract: Serum IgG, IgA and IgM levels of 91 patients with alveolar echinococcosis and 83 patients with cystic echinococcosis were compared with 104 healthy adults as controls by single radial immunodiffusion. The mean IgG, IgA and IgM concentrations in patients with alveolar echinococcosis and the mean IgG and IgM levels in patients with cystic echinococcosis were found to be significantly higher than those of the normal controls.The mean IgG, IgA and IgM levels in patients with alveococcosis were 510 ± 413.06, 389.45±433.42 and 313.48 ±255.19, while those in cystococcosis were 308.36±339.24, 329.61±319 and 266.68± 255.68 respectively.The geometric mean of IgG and IgM levels in patients with alveococcosis was 1.67 and 1.25 times that in cystococcosis. 76.9% of alveococcosis patients had IgG levels reaching 200 IU/ml or above, being significantly higher than that in the cystic hydati-dosis (50.6%). 93.4% of alveolar echinococcosis cases showed elevated IgM levels up to 100IU/ml or more, being also significantly higher than that of cystic echinococcosis cases (78.3).Statistically, there was significant correlation between IgG concentration and ELISA antibody titre.