中国寄生虫学与寄生虫病杂志 ›› 1988, Vol. 6 ›› Issue (S1): 159-159.

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Use of drug-carrier system in the treatment of Plasmodium berghei infected-mice.

  

  • 收稿日期:2017-01-10 修回日期:2017-01-10 出版日期:1988-12-30 发布日期:2017-01-10

  • Received:2017-01-10 Revised:2017-01-10 Online:1988-12-30 Published:2017-01-10

摘要: 359 mice infected with Plesmodium berghei were divided into 36 groups and treated with serialdosages of chloroquine entrapped in liposome.This drug-carrier system was compared with free chloro-quinn in another serial dosages.Five experiments were accomplished with various controls in each.Thetotal dosage for each mouse was divided into 2-3 parts i.p.cn Day 3,4 or Day 3,4,7.The percentagecf prolongation of the average life span(PALS)of mice was calculated according to the fourmula: