中国寄生虫学与寄生虫病杂志 ›› 1986, Vol. 4 ›› Issue (3): 209-211.

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甲苯咪唑和中药消包丸治疗57例包虫病的初步临床观察

蒋次鹏   

  1. 兰州医学院包虫病实验室
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1986-08-31 发布日期:2017-01-12

PRELIMINARY CLINICAL OBSERVATIONS ON MEBENDAZOLE AND TRADITIONAL CHINESE MEDICINE TREATMENT IN 57 CASES WITH ECHINOCOCCOSIS

  • Received:2017-01-12 Revised:2017-01-12 Online:1986-08-31 Published:2017-01-12

摘要: 用甲苯咪唑和中医药共治疗57例包虫病,其中囊型47例,泡型10例。分三组治疗,单服甲苯咪唑组20例,单服中药消包丸组23例,联合用药组14例。45例随访0.5~2.5年(平均1.2年),治愈率11.1%,好转率33.3%,稳定率24.4%,恶化率31.1%。

关键词: 包虫病, 甲苯咪唑, 临床观察, 联合用药组, 病理检查, 药物治疗, 中医药治疗, 肝泡型包虫病, 寄生虫病, 囊型包虫病

Abstract: From Aug. 1979 to Mar. 1983, mebendazole or/and traditional Chinese medicine were used to treat 57 cases with echinococcosis, of whom 47 were unilocular or cystic type (liver, lung, peritoneal cavity, heart and spinal vertebra) and the other 10 belonged to liver multilocular or alveolar type. 57 cases were divided into 3 groups: (1) mebendazole was given alone in 20 cases; (2) traditional Chinese medicine was given alone in 23 cases; and (3) combined medication of mebendazole and traditional Chinese medicine were used in 14 cases. Mebendazole was given 400-600mg each time in adult, t.i.d.. One pill (10g) of Chinese herbs was given 2 or 3 times per day. One therapeutic course lasted 4 weeks. Most of the cases received 2-3 courses and a few patients exceeded 6 courses. The curative effects are determined by clinical findings, x-ray examination, ultrasonic echogram, and macro- or micro-scopic observations of the operated specimens (hydatid endocyst), and then graded as cured, improved, stable and progressive. The rates of these grades were successively calculated as 11.1%, 33.3%, 24.4% and 31.1% from 45 cases followed up for 0.5-2.5 year.