中国寄生虫学与寄生虫病杂志 ›› 1984, Vol. 2 ›› Issue (3): 161-163.

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日本血吸虫病患者T淋巴细胞酸性α-醋酸萘酯酶活性变化的初步观察

傅翠娥,陈彩华,查鑑良,范黎   

  1. 浙江人民卫生实验院寄生虫病研究所
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1984-08-31 发布日期:2017-01-12

PRELIMINARY OBSERVATION ON THE ACTIVITY OF T LYMPHOCYTE ACID α-NAPHTHYL ACETATE ESTERASE IN BLOOD OF PATIENTS WITH SCHISTOSOMISIS JAPONICA

  • Received:2017-01-12 Revised:2017-01-12 Online:1984-08-31 Published:2017-01-12

摘要: 本文报告日本吸血虫病患者T淋巴细胞酯酶标记试验的酸性α-醋酸萘酯酶(ANAE)阳性百分率和淋巴细胞转化试验的淋巴细胞转化率较正常人均有下降趋势,且两法的测定结果是相关的。初步认为酯酶标记试验测定T淋巴细胞ANAE阳性率高低可作为估价日本血吸虫病患者细胞免疫功能的一种参考指标。

关键词: 日本血吸虫病, T淋巴细胞, 酸性α-醋酸萘酯酶, 细胞免疫功能, 淋巴细胞转化率, 淋巴细胞转化试验, 初步观察, 活性变化, 淋转率, 寄生虫病研究所

Abstract: 31 blood samples from proven patients with chronic schistosomiasis, 35 from the late stage patients, and 37 from healthy persons were tested by both T lymphocyte esterase label test and lymphocyte transfoamion test (LTT). Both ANAE-label test positivity rate and lymphocyte transformation rate were significantly lower in the schistosomiasis patients than in the healthy persons. The results measured by both methods were closely related.It is preliminarily considered that the determination of blood ANAE activity may be taken as a reference index for the evaluation of cell immunity function of the patients with schistosomiasis.