中国寄生虫学与寄生虫病杂志 ›› 1984, Vol. 2 ›› Issue (3): 136-139.

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基本消灭血吸虫病地区连续五年的血清流行病学调查

李允鹤,杨光堡,殷水龙,胡永德,吴宗泉,钱铭,归福淳,郑效玉,吴建中   

  1. 苏州医学院寄生虫学教研室; 苏州医学院寄生虫学教研室; 苏州医学院寄生虫学教研室; 苏州医学院寄生虫学教研室; 苏州医学院寄生虫学教研室; 江苏省常熟市卫生防疫站血防科; 江苏省常熟市卫生防疫站血防科; 江苏省常熟市卫生防疫站血防科; 江苏省常熟市卫生防疫站血防科
  • 收稿日期:2017-01-12 修回日期:2017-01-12 出版日期:1984-08-31 发布日期:2017-01-12

FIVE YEAR SEROEPIDEMIOLOGICAL SURVEY IN AN AREA WITH SCHISTOSOMIASIS BASICALLY ERADICATED

  • Received:2017-01-12 Revised:2017-01-12 Online:1984-08-31 Published:2017-01-12

摘要: 在基本消灭血吸虫病地区应用环卵沉淀反应和酶标记抗原对流免疫电泳对219~453名粪检阴性包括有血吸虫病史者和无血吸虫病史者进行了连续五年的血清流行病学调查,结果表明两种血清学方法检测特异性抗体水平的动态变化,可反映流行区的疫情趋势、考核防治效果、提高病人检出率,有综合查病的诊断价值。

关键词: 血清流行病学调查, 血吸虫病人, 基本消灭, 阳性率, 环沉率, 抗体水平, 寄生虫学, 血清学方法, 寄生虫病研究所, 特异性抗体

Abstract: In an area with schistosomiasis basically eradicated, circumoval precipitin test (COPT) and enzyme-linked antigen counterimmunoelectrophoresis (ELACIEP) were used as means of seroepidemiological survey to measure the changes of the specific schis-tosome antibody levels for 5 consecutive years in 219-453 subjects having negative ova or miracidia for stool examinations. 60 cases with a history of previous treatment and 53 persons without therapeutic history were also observed by using these two serological methods. The results showed that both COPT and ELACIEP could reveal kinetic changes of specific schistosome antibody levels in seroepidemiological survey, and be used for evaluation of the efficacy of control. Both COPT and ELACIEP were of value in increasing the detecting rates of patients.