日本血吸虫蛋白质组学研究进展

doi:10.12140/j.issn.1000-7423.2021.06.002

中国寄生虫学与寄生虫病杂志 ›› 2021, Vol. 39 ›› Issue (6): 725-730.doi: 10.12140/j.issn.1000-7423.2021.06.002

日本血吸虫蛋白质组学研究进展

洪炀(), 林矫矫^*()

中国农业科学院上海兽医研究所国家动物血吸虫病参考实验室,中国农业科学院上海兽医研究所农业农村部动物寄生虫学重点实验室,上海 200241

收稿日期:2021-11-17 修回日期:2021-12-01 出版日期:2021-12-30 发布日期:2021-12-22
通讯作者: 林矫矫
作者简介:洪炀（1983-）,男,博士,副研究员,从事血吸虫蛋白组及分子生物学研究。E-mail： hongyang_7@126.com
基金资助:
国家重点研发计划(2017YFD0501306)

Research progress on proteomics in Schistosoma japonicum

HONG Yang(), LIN Jiao-jiao^*()

National Reference Laboratory for Animal Schistosomiasis, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology of Ministry of Agriculture and Rural Affairs, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China

Received:2021-11-17 Revised:2021-12-01 Online:2021-12-30 Published:2021-12-22
Contact: LIN Jiao-jiao
Supported by:
National Key Research and Development Program of China(2017YFD0501306)

摘要/Abstract

摘要：

蛋白是基因功能的主要体现者和具体实施者。近年来,日本血吸虫蛋白质组学研究受到关注并取得一些进展。本文对国内外在日本血吸虫蛋白质组学方面的研究进展作一综述,以期为阐述日本血吸虫的生长发育机制,筛选诊断抗原标识、疫苗候选分子和新治疗药物靶标等提供有参考价值的信息。

关键词: 日本血吸虫, 蛋白质组学, 生长发育机制

Abstract:

Protein is the major exhibiter and executer of gene function. In recent years, the proteomics studies of Schistosoma japonicum has attracted the attention of researchers and made some progress. This paper reviews the research progress in proteomics of S. japonicum to provide information of referential value for elaborating the mechanism of schistosome growth and development as well as screening potential diagnostic antigens, vaccine candidate molecules and new therapeutic drug targets.

Key words: Schistosoma japonicum, Proteomics, Mechanism of growth and development

中图分类号:

R382.24

洪炀, 林矫矫. 日本血吸虫蛋白质组学研究进展[J]. 中国寄生虫学与寄生虫病杂志, 2021, 39(6): 725-730.

HONG Yang, LIN Jiao-jiao. Research progress on proteomics in Schistosoma japonicum[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2021, 39(6): 725-730.

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日本血吸虫蛋白质组学研究进展

Research progress on proteomics in Schistosoma japonicum

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