疟疾和肠道菌群的相互影响

doi:10.12140/j.issn.1000-7423.2021.04.016

中国寄生虫学与寄生虫病杂志 ›› 2021, Vol. 39 ›› Issue (4): 520-525.doi: 10.12140/j.issn.1000-7423.2021.04.016

疟疾和肠道菌群的相互影响

钟秋婷¹(), 宋健平¹, 吕芳丽²^,³^,⁴^,^*()

1 广州中医药大学青蒿研究中心,广州 510405
2 中山大学中山医学院寄生虫学教研室,广州 510080
3 中山大学热带病防治研究教育部重点实验室,广州 510080
4 广东省媒介生物防控工程技术研究中心,广州 510080

收稿日期:2020-11-12 修回日期:2020-12-02 出版日期:2021-08-30 发布日期:2021-06-04
通讯作者: 吕芳丽
作者简介:钟秋婷（1996-）,女,硕士研究生,主要从事疟疾防治研究。E-mail： 1019746004@qq.com
基金资助:
国家自然科学基金面上项目(81971955);国家自然科学基金面上项目(81873218);广东省自然科学基金面上项目(2019A1515011667);广东省自然科学基金面上项目(2021A1515012115)

The interactions between malaria and gut microbiota

ZHONG Qiu-ting¹(), SONG Jian-ping¹, LV Fang-li²^,³^,⁴^,^*()

1 Artemisinin Research Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China
2 Department of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China
3 Key Laboratory of Tropical Disease of Ministry of Education, Sun Yat-sen University, Guangzhou 510080, China
4 Provincial Engineering Technology Research Center for Biological Vector Control, Guangzhou 510080, China

Received:2020-11-12 Revised:2020-12-02 Online:2021-08-30 Published:2021-06-04
Contact: LV Fang-li
Supported by:
Grants from the National Natural Science Foundation of China(81971955);Grants from the National Natural Science Foundation of China(81873218);Natural Science Foundation of Guangdong Province(2019A1515011667);Natural Science Foundation of Guangdong Province(2021A1515012115)

摘要/Abstract

摘要：

肠道是人体最庞大和最重要的微生态系统,肠道菌群与人体健康和各种疾病关系密切。本文对肠道菌群与疾病的关系,疟疾对肠道菌群的影响,包括胃肠型疟疾对肠道的损伤,疟疾引起的肠道菌群组成、比例和功能的变化;以及肠道菌群对疟疾的影响,包括肠道菌群对疟疾风险的影响、肠道菌群对疟疾转归的影响等进行综述,探讨疟疾与肠道菌群之间的相互关系,为预防和控制疟疾提供新的思路。

关键词: 疟疾, 肠道菌群, 相互影响

Abstract:

Intestine is the largest and most important micro-ecosystem in the human body, and gut microbiota is closely related to human health and various diseases. This review summarizes the relationship between gut microbiota and diseases, the impact of malaria on gut microbiota, including damage of gastrointestinal type malaria to the intestine, and alterations of the composition, constitution, and function of gut microbiota caused by malaria; and the impact of gut microbiota on malaria, including the impact of gut microbiota on the risk of malaria and the outcome of malaria. Exploring the interactions between malaria and gut microbiota may provide clues for prevention and control of malaria.

Key words: Malaria, Gut microbiota, Interaction

中图分类号:

R531.3

钟秋婷, 宋健平, 吕芳丽. 疟疾和肠道菌群的相互影响[J]. 中国寄生虫学与寄生虫病杂志, 2021, 39(4): 520-525.

ZHONG Qiu-ting, SONG Jian-ping, LV Fang-li. The interactions between malaria and gut microbiota[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2021, 39(4): 520-525.

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疟疾和肠道菌群的相互影响

The interactions between malaria and gut microbiota

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