青藏高原地区犬棘球绦虫感染的流行情况和影响因素

doi:10.12140/j.issn.1000-7423.2020.04.015

摘要/Abstract

摘要：

棘球蚴病是由棘球绦虫幼虫引起的人兽共患寄生虫病,在我国青藏高原地区广泛流行。犬是引起人棘球蚴病的重要传染源。青藏高原地区犬棘球绦虫感染情况严重。本文对青藏高原地区犬棘球绦虫感染的流行情况和影响因素进行综述。

Abstract:

Echinococcosis is a zoonotic disease caused by the larvae of the genus Echinococcus, which is widely prevalent in Qinghai-Tibet plateau of China. Canine is the major infection source of human echinococcosis, and canine infection with Echinococcus spp. has become a heavy burden in Qinghai-Tibet plateau. In this paper, we review the prevalence and impacting factors of canine infection with Echinococcus spp. in Qinghai-Tibet plateau.

Key words: Echinococcus, Canine, Prevalence, Influencing factors

中图分类号:

R532.32

崔小玉, 官亚宜, 伍卫平. 青藏高原地区犬棘球绦虫感染的流行情况和影响因素[J]. 中国寄生虫学与寄生虫病杂志, 2020, 38(4): 482-489.

CUI Xiao-yu, GUAN Ya-yi, WU Wei-ping. The prevalence and impacting factors of Echinococcus infection in canine in Qinghai-Tibet plateau[J]. Chinese Journal of Parasitology and Parasitic Diseases, 2020, 38(4): 482-489.

参考文献 52

[1]	Wu WP, Wang H, Wang Q, et al. A nationwide sampling survey on echinococcosis in China during 2012-2016[J]. Chin J Parasitol Parasit Dis, 2018,36(1):1-14. (in Chinese)
	( 伍卫平, 王虎, 王谦, 等. 2012-2016年中国棘球蚴病抽样调查分析[J]. 中国寄生虫学与寄生虫病杂志, 2018,36(1):1-14.)
[2]	Eckert J, Gemmell MA, Meslin FX, et al. WHO/OIE manual on echinococcosis in humans and animals: a public health problem of global concern[J]. Int J Parasit, 2001,31(14):1717-1718. doi: 10.1016/S0020-7519(01)00318-6
[3]	Liu H, Xiao N, Yang SJ, et al. Epidemiological characteristics of canine Echinococcus infection in Qinghai Tibet Plateau of China[J]. Chin J Schisto Control, 2017,29(2):129-138. (in Chinese)
	( 刘辉, 肖宁, 杨诗杰, 等. 青藏高原地区犬棘球绦虫感染的流行病学特征[J]. 中国血吸虫病防治杂志, 2017,29(2):129-138.)
[4]	Wang GQ. Epidemiological survey on echinococcosis in China[M]. Shanghai: Shanghai Scientific & Technical Publishers, 2016. (in Chinese)
	( 王国强. 全国包虫病流行情况调查报告[M]. 上海: 上海科学技术出版社, 2016.)
[5]	He W, Shang JY, Huang Y, et al. Surveillance of hydatidosis in Sichuan, 2007-2013[J]. J Prev Med Inf, 2016,32(8):798-800. (in Chinese)
	( 何伟, 尚婧晔, 黄燕, 等. 2007-2013年四川省包虫病疫情监测结果分析[J]. 预防医学情报杂志, 2016,32(8):798-800.)
[6]	Wang H, Ma JY, Han XM, et al. A survey and analysis on echinococcosis in Guoluo Prefecture of Qinghai Province[J]. Chin J Endemiol, 2007,26(5):553-556. (in Chinese)
	( 王虎, 马俊英, 韩秀敏, 等. 青海省果洛州人与动物棘球蚴病调查[J]. 中国地方病学杂志, 2007,26(5):553-556.)
[7]	Ma X, Wang H, Zhang JX, et al. Epidemiological investigation on hydatid disease/echinococcosis in Guoluo Tibetan Autonomous Prefecture in Qinghai Province[J]. Chin J Parasitol Parasit Dis, 2017,35(4):366-370. (in Chinese)
	( 马霄, 王虎, 张静宵, 等. 青海省果洛藏族自治州棘球蚴病和棘球绦虫病流行情况调查[J]. 中国寄生虫学与寄生虫病杂志, 2017,35(4):366-370.)
[8]	Kan W, Zhao QB, Ma RL, et al. An investigation on dog echinococcus infections in Qinghai Province[J]. Chin J Vet Med, 2017,53(1):45-47. (in Chinese)
	( 阚威, 赵全邦, 马睿麟, 等. 青海地区犬感染棘球绦虫的调查[J]. 中国兽医杂志, 2017,53(1):45-47.)
[9]	Guo HW, He CJ, Bao SK, et al. Long-term effect test of echinococcosis comprehensive control in Haibei Prefecture[J]. Chin Qinghai J Anim Vet Sci, 2004,34(1):51. (in Chinese)
	( 郭红玮, 何成基, 保善科, 等. 海北州棘球蚴病综合防治远期效果检测[J]. 青海畜牧兽医杂志, 2004,34(1):51.)
[10]	Wang YS, Ma X, Han XM, et al. Prevalence of echinococcosis in Haibei Tibetan Autonomous Prefecture in Qinghai[J]. Chin J Pathogen Biol, 2017,12(5):441-443. (in Chinese)
	( 王永顺, 马霄, 韩秀敏, 等. 青海省海北藏族自治州棘球蚴病流行现状调查[J]. 中国病原生物学杂志, 2017,12(5):441-443.)
[11]	Liu XT. Discussion on the prevalence and prevention of human parasitic diseases in Tibet[J]. Tibet Sci Technol, 2010,35(4):34-36, 43. (in Chinese)
	( 刘晓堂. 西藏人体寄生虫病的流行与防治探讨[J]. 西藏科技, 2010,35(4):34-36, 43.)
[12]	Kangzhu YX, Zheng CJ, He RF, et al. Investigation of Echinococcus infection in dogs in Tibet Autonomous Region[J]. Chin J Parasitol Parasit Dis, 2018,36(1):35-37. (in Chinese)
	( 康珠益西, 郑灿军, 何瑞峰, 等. 西藏自治区犬棘球绦虫感染现状调查与分析[J]. 中国寄生虫学与寄生虫病杂志, 2018,36(1):35-37.)
[13]	Ma YA, Shang WJ. Endemic situation of echinococcosis in Gannan Tibetan Autonomous Prefecture[J]. Chin J Parasitol Parasit Dis, 2015,33(5):352-356. (in Chinese)
	( 马玉安, 尚文杰. 甘南藏族自治州棘球蚴病流行情况分析[J]. 中国寄生虫学与寄生虫病杂志, 2015,33(5):352-356.)
[14]	Yang YM, Wang LB, Wu FW, et al. Survey of echinococcosis prevalence in area neigbouring Tibet in Yunnan[J]. Dis Surv, 2014,29(1):52-55. (in Chinese)
	( 杨亚明, 汪丽波, 吴方伟, 等. 青藏高原向云南延伸地区包虫病现状调查[J]. 疾病监测, 2014,29(1):52-55.) doi: 10.3784/j.issn.1003-9961.2014.01.014
[15]	Li BF, Wu FW, Yan XL, et al. Epidemiology analysis of echinococcosis in Yunnan Province from 2012 to 2017[J]. Chin J Parasitol Parasit Dis, 2019,37(5):576-582. (in Chinese)
	( 李奔福, 吴方伟, 严信留, 等. 2012-2017年云南省棘球蚴病流行病学分析[J]. 中国寄生虫学与寄生虫病杂志, 2019,37(5):576-582.)
[16]	Guo L, Yang AG, Zhang ZZ, et al. An epidemiological survey on livestock hydatid diseases in Sichuan Province[J]. Chin J Vet Med, 2012,48(2):25-27. (in Chinese)
	( 郭莉, 阳爱国, 张壮志, 等. 四川省家畜包虫病流行病学调查报告[J]. 中国兽医杂志, 2012,48(2):25-27.)
[17]	Guo HW, Hu Y, Bao GQ, et al. Population and application of synthetical prevention and therapeutic technology for echinococcosis[J]. Chin Qinghai J Animal Vet Sci, 1999,29(5):3-6. (in Chinese)
	( 郭红玮, 胡义, 保广祺, 等. 棘球蚴病综合防治技术推广应用[J]. 青海畜牧兽医杂志, 1999,29(5):3-6.)
[18]	Yu WJ, Huang L, Huang Y, et al. Seasonal infection pattern of dogs in endemic area of alveolar echinococcosis, Western Sichuan Province, China[J]. Chin J Zoonoses, 2013,29(3):309-311. (in Chinese)
	( 喻文杰, 黄亮, 黄燕, 等. 四川省西部藏族地区包虫病流行区犬只感染棘球绦虫季节性规律研究[J]. 中国人兽共患病学报, 2013,29(3):309-311.) doi: 10.3969/cjz.j.issn.1002-2694.2013.03.021
[19]	Seres S, Avram E, Cozma V. Coproantigen prevalence of Echinococcus spp. in rural dogs from Northwestern Romania[J]. Sci Parasitol, 2010,11(3):165-169.
[20]	Buishi IE, Njoroge EM, Bouamra O, et al. Canine echinococcosis in northwest Libya: assessment of coproantigen ELISA, and a survey of infection with analysis of risk-factors[J]. Vet Parasitol, 2005,130(3):223-232. doi: 10.1016/j.vetpar.2005.03.004
[21]	Budke CM, Campos-Ponce M, Qian W, et al. A canine purgation study and risk factor analysis for echinococcosis in a high endemic region of the Tibetan plateau[J]. Vet Parasitol, 2005,127(1):43-49. doi: 10.1016/j.vetpar.2004.08.024 pmid: 15619374
[22]	Huang Y, David HD, Yang W, et al. Epidemiology and risk factor analysis for canine echinococcosis in a Tibetan pastoral area of Sichuan[J]. Chin J Parasitol Parasit Dis, 2008,26(4):245-252. (in Chinese)
	( 黄燕, David HD, 杨文, 等. 四川省藏族牧区家犬棘球绦虫病流行病学调查研究(英文)[J]. 中国寄生虫学与寄生虫病杂志, 2008,26(4):245-252.)
[23]	Chen J. Specific detection of the prevalence of Echinococcus in Tibetan foxes with fecal DNA[D]. Shanghai: East China Normal University, 2014. (in Chinese)
	( 陈珏. 基于粪便DNA调查藏狐的棘球绦虫感染率[D]. 上海: 华东师范大学, 2014.)
[24]	Wang H, Chai JJ, Liu FJ, et al. A study on ecological-epidemiology of two hydatid disease in Qinghai[J]. Chin J Parasit Dis Control, 2002,15(5):32-35. (in Chinese)
	( 王虎, 柴君杰, 刘凤洁, 等. 青海省包虫病的生态流行病学研究[J]. 中国寄生虫病防治杂志, 2002,15(5):32-35.)
[25]	Craig P, Liu D, Macpherson C, et al. A large focus of alveolar echinococcosis in central China[J]. Lancet, 1992,340(8823):826-831. doi: 10.1016/0140-6736(92)92693-a pmid: 1357252
[26]	Zhao YM, Chong SG, Liang Z, et al. Infective situation of Echinococcus in dogs in Gannan Tibetan Autonomous Prefecture[J]. Chin J Pathogen Biol, 2009,4(2):124-125, 136. (in Chinese)
	( 赵玉敏, 种世桂, 梁忠, 等. 甘南藏族自治州终末宿主犬感染棘球绦虫状况调查[J]. 中国病原生物学杂志, 2009,4(2):124-125, 136.)
[27]	Yan JJ, Zhang Y, Cai ZY, et al. Analysis on the human- wildlife conflict in the Sanjiangyuan Region[J]. Acta Theriologica Sinica, 2019,39(4):476-484. (in Chinese)
	( 闫京艳, 张毓, 蔡振媛, 等. 三江源区人兽冲突现状分析[J]. 兽类学报, 2019,39(4):476-484.)
[28]	WHO. Neglected tropical diseases: global impact and countermeasures(translation published)[M]. Beijing: People’s Medical Publishing House, 2011. (in Chinese)
	( 世界卫生组织. 被忽视的热带病: 全球影响与防治对策(译书出版)[M]. 北京: 人民卫生出版社, 2011.)
[29]	Colli CW, Williams JF. Influence of temperature on the infectivity of eggs of Echinococcus granulosus in laboratory rodents[J]. J Parasitol, 1972,58(3):422-426. pmid: 5064968
[30]	Wachira TM, Macpherson CNL, Gathuma JM. Hydatid disease in the Turkana District of Kenya, Ⅶ: analysis of the infection pressure between definitive and intermediate hosts of Echinococcus granulosus, 1979-1988[J]. Pathog Glob Health, 84(4):361-368.
[31]	Xu X. Study on distribution and infection of intermediate host with in high epidemic areas of alveolar hydatid disease[D]. Beijing: Chinese Center For Disease Control And Prevention. 2008. (in Chinese)
	( 许翔. 泡型包虫病高流行区多房棘球绦虫中间宿主分布及感染状况的研究[D]. 北京: 中国疾病预防控制中心, 2008.)
[32]	Wang Q, Budke CM, Huang L, et al. Spatial clustering of E. multilocularis infected dogs in pastoral Tibetan communities, Sichuan, China[J]. J Prev Med Inf, 2012,28(5):323-328. (in Chinese)
	( 王谦, 克莉丝汀·布德克, 黄亮, 等. 四川省藏族牧区感染多房棘球绦虫犬只空间聚集性研究[J]. 预防医学情报杂志, 2012,28(5):323-328.)
[33]	Guo ZX, He DL, Li YQ, et al. Infection of Echinococcus species in wild animals in Qinghai Province[J]. Chin J Parasitol Parasit Dis, 1994,12(S1):145-147. (in Chinese)
	( 郭再宣, 何多龙, 李予青, 等. 青海高原野生动物棘球绦虫感染情况的调查[J]. 中国寄生虫学与寄生虫病杂志, 1994,12(S1):145-147.)
[34]	Wu HS, Yang N, Chen HJ, et al. Investigation on hydatid disease and surface parasites of Tibetan antelope[J]. Chin Qinghai J Anim Vet Sci, 2009,39(6):28-29. (in Chinese)
	( 吴海生, 杨宁, 陈洪舰, 等. 藏羚羊包虫病及体表寄生虫调查报告[J]. 青海畜牧兽医杂志, 2009,39(6):28-29.)
[35]	Cai HX, Wang H, Han XM, et al. Current situation of Echinococcus infection in different hosts in Qinghai plateau[J]. Chin J Endemiol, 2012,31(3):296-300. (in Chinese)
	( 蔡辉霞, 王虎, 韩秀敏, 等. 青海高原棘球绦虫不同宿主感染情况及意义的研究[J]. 中国地方病学杂志, 2012,31(3):296-300.)
[36]	Wang Q, Raoul F, Budke C, et al. Grass height and transmission ecology of Echinococcus multilocularis in Tibetan communities, China[J]. Chin Med J, 2010,123(1):61-67. pmid: 20137577
[37]	Guzel M, Yaman M, Koltas IS, et al. Detection of Echinococcus granulosus coproantigens in dogs from Antakya Province, Turkey[J]. Helminthologia, 2008,45(3):150-153. doi: 10.2478/s11687-008-0030-3
[38]	Wanma C. Strictly control the number of dogs in pastoral area to ensure people and animals health[J]. Chin J Anim Husb Vet Med, 2008,24(9):31. (in Chinese)
	( 万玛措. 严格控制牧区养犬数量, 保障人畜健康[J]. 畜牧兽医科技信息, 2008,24(9):31.)
[39]	Yin H, Lu Z, Wang Y, et al. The Tibetan mastiff economy crashed survey on stray dogs in plateau[J]. Cul Geogra, 2017,10(23):44-53. (in Chinese)
	( 尹杭, 路子, 王郢, 等. 藏獒经济崩盘高原流浪狗问题调查[J]. 环球人文地理, 2017,10(23):44-53.)
[40]	Li T. The price of Tibetan mastiff and cordyceps soared after Yushu earthquake[J]. Rural Best Tone, 2010,29(11):25. (in Chinese)
	( 林涛. 玉树地震后藏獒虫草价狂升[J]. 农村百事通, 2010,29(11):25.)
[41]	Liu HM, Li LH, Cheng L. Calm evaluation on Chinese Tibetan mastiff market after experiencing the boom[J]. Chin Tibet, 2015,27(3):24-25. (in Chinese)
	( 刘洪明, 李琳海, 程露. 冷观经历热炒后的中国藏獒市场[J]. 中国西藏, 2015,27(3):24-25.)
[42]	Hu GW. Detection of fecal antigen by ELISA to investigate the dog infections of Echinococcus granulosus in Yushu[C]// The 13th academic symposium proceedings of the Veterinary Parasitology Branch of the Chinese Society of Animal Science and Veterinary, Harbin, 2015. (in Chinese)
	( 胡广卫. ELISA检测粪抗原调查玉树地区犬细粒棘球绦虫感染情况[C] //中国畜牧兽医学会兽医寄生虫学分会第十三次学术研讨会论文集, 哈尔滨, 2015.)
[43]	Wang H. Analysis on risk factors of human hydatidosis in Qinghai Province[J]. Chin J Parasit Dis Control, 2004,17(4):28-30. (in Chinese)
	( 王虎. 青海省人体包虫病风险因素分析[J]. 中国寄生虫病防治杂志, 2004,17(4):28-30.)
[44]	Lei ZL, Wang LY. Control situation and primary task of key parasitic diseases in China[J]. Chin J Parasitol Parasit Dis, 2012,30(1):1-5. (in Chinese)
	( 雷正龙, 王立英. 全国重点寄生虫病防治形势与主要任务[J]. 中国寄生虫学与寄生虫病杂志, 2012,30(1):1-5.)
[45]	Yang W. Epidemic status and control measures of hydatidosis in Sichuan Tibetan areas[C] //Proceedings of the national symposium on zoonosis prevention and control. Chinese Preventive Medicine Association, Beijing, 2006.
	( 杨文. 四川藏区包虫病流行现状与防治对策[C] //全国人畜共患病学术研讨会论文集, 北京, 2006.)
[46]	Li W, Xu KJ, Xu GR, et al. Current status on prevalence and control of echinococcosis in Ganzi Tibetan Autonomous Prefecture[J]. Int J Med Parasit Dis, 2011,38(5):315-317. (in Chinese)
	( 李伟, 徐克均, 许光荣, 等. 甘孜藏族自治州棘球蚴病的流行和防控现状[J]. 国际医学寄生虫病杂志, 2011,38(5):315-317.)
[47]	Xu LQ, Chen YD, Sun FH, et al. National investigation report on the status of human important parasitic diseases[J]. Chin J Parasitol Parasit Dis, 2005,23(S1):332-340. (in Chinese)
	( 许隆祺, 陈颖丹, 孙凤华, 等. 全国人体重要寄生虫病现状调查报告[J]. 中国寄生虫学与寄生虫病杂志, 2005,23(S1):332-340.)
[48]	Buishi I, Walters T, Guildea Z, et al. Reemergence of canine Echinococcus granulosus infection, Wales[J]. Emerging Infect Dis, 2005,11(4):568-571. doi: 10.3201/eid1104.040178 pmid: 15829195
[49]	Economides P, Christofi G, Gemmell MA. Control of Echinococcus granulosus in Cyprus and comparison with other island models[J]. Vet Parasitol, 1998,79(2):151-163. doi: 10.1016/s0304-4017(98)00163-0 pmid: 9806495
[50]	Polydorou K. Echinococcosis/hydatidosis eradication campaign in Cyprus[J]. Kenya Vet, 1994,18(2):543.
[51]	Economides P, Christofi G. Evaluation of control programmes for echinococcosis/hydatidosis in Cyprus[J]. Rev Sci Tech, 2000,19(3):784-792. doi: 10.20506/rst.19.3.1252 pmid: 11107621
[52]	Zhu YY, Wu WP. Advances in echinococcosis prevention and control programs and research in China and elsewhere around the world[J]. Chin J Pathogen Biol, 2016,11(3):284-286, 289. (in Chinese)
	( 朱曜宇, 伍卫平. 国内外包虫病防治和研究进展[J]. 中国病原生物学杂志, 2016,11(3):284-286, 289.)